For treatment of 40 patients with non-specific colpitis we used a method of streaming ozone therapy with assistance of the ozone generator MEDOZONS-BM and special attachment on the basis of vaginal speculum. The irrigation with an ozone-oxygen mixture with ozone concentration of 2000 mcg/L was carried out within 5 minutes after preliminary moistening of mucosa with sterile distilled water.

In the course of investigations it was established that along with a positive clinical effect ozone therapy caused an improvement in vaginal local immunity indices – a credible increase in lysozyme in 70% of patients, a decrease in IgG level in 60% of patients, stabilization of cervical mucus myeloperoxidase in 80% of patients.