80 pregnant women with threatened abortion of infectious (40) and endocrine (40) genesis were treated with medical ozone. We established the following laboratory
changes:

– The study of lipid peroxidation processes on the background of ozonetherapy showed a decrease in the primary and secondary molecular products. The average 22,1% increase in the total antioxidative plasma activity was established.

– The patients treated with ozone showed an average week’s increase in progesterone concentration 3,3 times higher, in placental lactogen 2,4-3,6 times higher as compared with the conventional treatment.

– After using ozonetherapy, we established a credible decrease (by 20-50%) in circulating immune complexes. That correlated with intensification of the phagocytic activity. The level of IgM had a tendency to normalize.

Thus, owing to its varied positive effects on pregnant women ozonetherapy has proved to be an effective method of treatment and prophylaxis of threatened abortion.