Obesity is known to cause multiple complications in the course of pregnancy and labor activity. Conventional preventive methods do not seem to provide the expectant efficiency.

118 pregnant women with various stage of alimentary obesity were examined. The first group (71 patient) received ozone therapy, as a part of a complex treatment, in the form of intravenous infusions of ozonated saline (ozone concentration in ozone-oxygen mixture — 400 mcg/l) daily for 5 days. The second group (47 patients) was on conventional treatment. In the first group there were registered an increase in the activity of antioxidative enzymes as well as a decrease in the total serum lipids, normalization of blood coagulation in women with hypercoagulation. On comparing the course of pregnancy and labor activity in the two groups of patients an evident positive clinical effect of ozone therapy was elicited. Ozone-treated patients had lower rates of gestosis, premature delivery, prolonged gestation, powerless labor activity.

Thus, the received data let us consider ozone therapy as a promising preventive method in a combined treatment of patients with the excess of the body weight.