Mode of Action – Library of Medical Research

Low-Dose Medical Ozone as a Bioregulator. “Ozone Peroxide” as Second Messenger Molecule?

Introduction Three mechanisms of action are discussed as underlying effects of the efficacy of Medical Ozone in the form of Major Auto Hemotherapy MAH and rectal insufflation following the low- dose-concept. The classical indications and the corresponding ozone effects are listed in table 1. Indications Underlying Mechanisms of Action 1 Angiopathia,diabetic angiopathia in particular Arterial circulatory disorders Activation of RBC metabolism with an improvement of oxygen releaseActivation of ROS (reactive oxygen species) and radical

The Mechanism of the Anti-Inflammatory Effect of Ozonated Physiological Saline

The ozonated 0,9% sodium chlorid solution barbotaged in a standard bottle by ozone-oxygen mixture with ozone concentration of 1200 mcg/L for 15-20 minutes at flow rate 1 L/min produces a positive effect on the clinical course of acute PID and on some indices of the homeostasis in the given group of patients when introduced intravenously. The fungicidal and bactericidal effects of ozonated saline have not been established during the experiments in vitro on pure cultures

Ozone as a modulator of the immune system

In order to clarify the immunomodulating properties of ozone, we have investigated: a) the effects of stimulation on isolated peripheral human blood mononuclear cells (PBMC) from normal donors with either ozone or ozonated serum; b) the range (in terms of O3 concentrations) of the therapeutic window; c) the stimulatory and toxic effects and d) the pattern, of both proinflammatory and immunosuppressive cytokine production up to 86 hours after exposure to O3. Results show that ozone

Changes In Biochemical Characteristics In Correction Of Metabolic Misbalance With Low Doses Of Ozone

Introduction Metabolic syndrome (MS) is a complex disease caused by a combination of genetic factors with a person’s life-style (nutrition characterized by a high content of carbohydrates, hypodynamia and hypokinesia, alcohol, smoking, mental and physical strain). The incidence of metabolic syndrome in different countries ranges from 10% to 30%. In Russia about 1,200,000 people die annually as a result of MS complications. MS incidence has been found to be increasing in female patients for the

Milestones of Medical Ozone

Medical Ozone as a Focal Point of Criticism If we could either press medical ozone into tablets, pack them at the right dosages, or store it in the form of stable infusion solutions, or even sell it as an OTC product — many of our problems would be solved. Since its discovery by SCHÖNBEIN in 1839, ozone, and particularly medical ozone, has always had a negative image. This was why, already in 1935, JUSTUS

Ozone as a Regulator of Physiological Processes in the Organism

An attempt to explain therapeutic efficacy of low doses of ozone due to its trigger properties has been made in the present article. The model of hypoxia in dogs has been used to reveal H+-ATP-ase activation This enzyme provides the conjugation of respiration and oxidative phosphorylation. There has been demonstrated activation of K+ -Na+ -ATP-ase which is responsible for concentration gradient of K+ and Na+ in intra- and intercellular space and, hence, for electric potential

Library of Medical Research

Category: Mode of Action