The ozonated 0,9% sodium chlorid solution barbotaged in a standard bottle by ozone-oxygen mixture with ozone concentration of 1200 mcg/L for 15-20 minutes at flow rate 1 L/min produces a positive effect on the clinical course of acute PID and on some indices of the homeostasis in the given group of patients when introduced intravenously.

The fungicidal and bactericidal effects of ozonated saline have not been established during the experiments in vitro on pure cultures of Staphilococcus aureus CCM 885 gram-positive bacteria, Escherichia coli M-17 gram-negative bacilli and Candida albicans yeast-like fungi.

The study of the spontaneous (SCL) and induced chemiluminescence (ICL) parameters of neutrophiles in patients with acute PID testifies to the ability of ozonides to stimulate the function of polymorphonuclear leukocytes.